The invention discloses a system for realizing inter-DC end-to-end quality guarantee based on SR and ESI. The system comprises a plurality of DC network ends, three underlay networks are isolated between any two DC network ends; when any DC1 network end performs the communication of an encapsulated VXLAN data packet to another DC2 network end, the data packet enters the VTEP through a CE of the DC1 network end, enters the DCI through the VTEP, and then enters the DCI of the DC2 network end through the underlay, enters the VTEP through the DCI, and then enters the CE of the DC2 network end to accomplish the communication. The SR technology is configured in the underlay network between any two DCs, the fast rerouting is realized, and the access quality of a wide area network between the DCsis protected; in the overlay network, the ESI technology is configured at the VTEP and the DCI so as to realize the end-to-end redundancy protection from DC to DC.