The invention relates to a high-heat-resistant and high-strength semi-aromatic polyamide/polyester alloy material. The alloy material comprises the following components in percentages by weight: 20-70% of semi-aromatic polyamide, 10-50% of a polyester, 0.1-4% of a mixture composed of an aminobenzenesulfonic acid compound and an alcohol amine compound, 10-50% of a reinforcing agent, and 0.1-30% ofan auxiliary agent. The invention also provides a preparation method and application of the above alloy material. The high-heat-resistant and high-strength semi-aromatic polyamide/polyester alloy material provided by the invention has the advantages of high strength, good toughness, good dimensional stability and the like, and particularly has excellent heat resistance; the long-term heat-resistant temperature is higher than 150 DEG C, and when the alloy material is maintained under high-temperature condition of 150 DEG C for 1000 h, the tensile strength retention rate of the material is greater than 90%; the material is suitable for coil bobbins, connectors and engine peripheral components; and the material has a simple formula and preparation process, and low costs.