The invention discloses a wire coil fall-off prevention emergency stop device, which comprises a wire coil fall-off induction vertical rod, wherein the wire coil fall-off induction vertical rod is connected with a horizontal cross rod by means of a connecting shaft, the other end of the horizontal cross rod is provided with a frame stranding machine fixing connection part, a frame stranding machine emergency stop switch is fixedly arranged above the horizontal cross rod, and the frame stranding machine emergency stop switch and the wire coil fall-off induction vertical rod are positioned in the same vertical plane. The device capable of realizing frame stranding machine wire coil fall-off prevention emergency stop is provided by the invention, solves the problem that a frame stranding machine wire coil is prone to fall off during the wire stranding process, and starts the emergency stop device the first time by means of the wire coil fall-off induction vertical rod when the frame stranding machine wire coil falls off, so that the frame stranding machine stops operation timely, thereby preventing damage to the frame stranding machine and the personnel by the side and the occurrenceof production safety accidents because the frame stranding machine operates continuously after the wire coil falls off.