The invention provides an uplink power control method used for LTE communication system. The method comprises the steps of: configuring timers for each transmit power control group tpc-group and included user UE by a base station side, and updating in real time according to business state of the UE when dispatching; according to the timers, selecting and adding the tpc-group that satisfies the condition into a candidate list; according to a size sorting result, dispatching rest CCE (Control Channel Element) resource for corresponding tpc-group in sequence after the dispatch is finished; and, issuing TPC (Transmit Power Control) command words. The TPC command words are the transmit power control command words. By adoption of the method, in the scenario of having no uplink/downlink authorization to issue the TPC command words when the user has no uplink/downlink service in a period of time, the suitable tpc-group is selected to issue the TPC command words, so as to make full use of the channel resource, reduce the signaling overheads, and effectively and timely adjust the uplink transmit power to ensure the uplink/downlink throughput of the base station.