The invention belongs to the technical field of ground foundation engineering, and relates to an open-mouthed prestressed high-strength concrete tubular pile and anti-floating anchor integrated anti-floating method. Nonmetal materials with good corrosion resistance and high tensile strength serve as anti-floating anchor bodies, the anti-floating anchors are connected with prestressed high-strengthconcrete tubular piles, thus, the prestressed high-strength concrete tubular piles and the anti-floating anchors are connected integrally, construction procedures are reduced, the construction periodis shortened, the cost is reduced, and the prestressed high-strength concrete tubular piles not only can resist vertical pressure, but also can resist buoyancy of underground water.