The invention relates to a high-entropy alloy coating for thermal insulation protection, belonging to the technical field of a surface coating. High-entropy alloy powder prepared by a gas atomizationmethod is selected as a raw material, and the alloy powder which has good degree of sphericity and the particle size being 15-70 mu m is selected. The high-entropy alloy coating is prepared by an atmospheric plasma spraying method. The prepared coating maintains a good coating structure, high hardness and high toughness at medium and high temperatures and meanwhile has low and stable heat conductivity. The high-entropy alloy coating can be applied to the field of thermal insulation protection of a surface.