The invention discloses a closed type heat insulation and cooling sealed barrel. The closed type heat insulation and cooling sealed barrel comprises a barrel body and a filling layer. The closed typeheat insulation and cooling sealed barrel is characterized in that the barrel body is formed by an inner barrel, an outer barrel and a sealing cover in a sleeving manner. The filling layer is arrangedbetween the inner barrel and the outer barrel. The filling layer comprises a heat insulation and cooling layer, a buffer layer, a sealing layer and a protective layer. The heat insulation and coolinglayer is arranged as the first layer, the buffer layer is arranged as the second layer, the sealing layer is arranged as the third layer, and the protective layer is arranged as the fourth layer. A detection sensor is installed on the barrel body and used for detecting the internal temperature of the barrel and airtightness. The closed type heat insulation and cooling sealed barrel is simple in structure, convenient to maintain, low in cost, reliable in protection, and good in airtightness, and is an ideal container for chemical storage and transportation.