The invention provides a synthetic process of a compound and particularly provides a method for preparing a compound in a formula I through the compound. The definition of each of groups is describedin the Specification. A route of the preparation method provided by the in invention has the characteristics of industrialized production, high yield, easy separation of products and the like; the compound synthesized by the method provided by the invention is a multi-target tyrosine protein kinase inhibitor and has good anti-tumor activity.