The invention provides an intelligent dust removal and cooling device for a mine. The intelligent dust removal and cooling device comprises an intelligent sensing control system, a dust removal device, a cooling device and a water inlet device. The intelligent sensing control system comprises a sensing device and a control device, wherein the sensing device is used for collecting environmental information, and the control device obtains a control command according to the environmental information operation and executes the command. The dust removal device includes a dust removal water pipe anda spray device, and the spray device enables water to form mist and sprays the mist into the environment to reduce dust. The cooling device comprises a box body and a cooling water pipe, a wind pressure controller is arranged at an air inlet of the box body, heat change between hot air sucked from the environment and the cooling water pipe is performed, and after the temperature is lowered, the air is blown out from an air outlet. The water inlet device is provided with a water pressure controller which supplies cold water to the dust removal water pipe and the cooling water pipe, a dust removal valve is arranged at the position, connected to the dust removal water pipe, of the water inlet pipe, and a cooling valve is arranged at the position, connected to the cooling water pipe, of the water inlet pipe. Working parameters of the water pressure controller and the wind pressure controller are controlled by the control device according to the command, opening and closing of the dust removal valve and the cooling valve are controlled by the control device according to the command, and intelligent dust removal and cooling treatment are realized.