The invention provides a heating and cooling regulator. The heating and cooling regulator comprises a box body, a storage battery, refrigeration devices, a ventilation fan and a temperature controller, wherein the storage battery is located at the central portion of the box body; a heat insulation layer is arranged between the storage battery and the box body; the refrigeration devices are arranged between the ventilation fan and the storage battery; the ventilation fan is connected with a power supply via the temperature controller; and the number of the refrigeration devices is preferably four, and the refrigeration devices are evenly arranged along the inner wall of the box body and are preferably semiconductor chilling plates. With such a design, the heating and cooling regulator of the invention not only has strong cooling effect and good monitoring effect, but also is easy to install and use and wide in an application scope.