The invention discloses a medical foam box having a sterilization effect. The medical foam box having the sterilization effect comprises a box and an upper cover. A containing cavity is formed in thebox. A sliding type partition plate is arranged in the box at the middle position. The containing cavity is portioned into two storage cavities by the sliding type partition plate. The two sides of the lower end of the sliding type partition plate are both movably provided with ice rafts. The connection portions between the ice rafts and the sliding type partition plate are provided with connection blocks. The middle portion of the side, far away from the sliding type partition plate, of each raft is provided with a filling opening. The sliding type partition plate is provided with a pluralityof connection groove holes. According to the medical foam box having the sterilization effect, the inner portion of the box is divided into the two storage cavities through the sliding type partitionplate; due to use of the ice drafts, refrigerated transportation of various biological reagents, medicine and the like can be effectively achieved; L-shaped fixing feet achieve the protective function on the four corners of the box bottom; due to design of lifting holes, the box is convenient to carry; and therefore a better use prospect is brought.