利索-全球专利检索

  1. 登录
  2. 注册
发明公开
CN108727486A 长效神经生长因子、制备方法及其组合物 审中-实审

长效神经生长因子、制备方法及其组合物
摘要：
本发明提供了一种长效神经生长因子，其包含第一个多肽，该多肽具有N末端和与具有N末端和C末端的第二个多肽融合的C末端，其特征在于：第一个多肽是神经生长因子，并且第一个多肽的C末端与第二个多肽的N末端融合后得到的长效神经生长因子，所述长效神经生长因子具有超过14小时的体内半衰期，且生物活性较高。
摘要（英）：

The invention provides a long-acting nerve growth factor which comprises a first polypeptide, wherein the polypeptide is provided with a tail end N and a tail end C which is fused with a second polypeptide with the tail end N and the tail end C. The long-acting nerve growth factor is characterized in that the first polypeptide is the nerve growth factor, and the tail end C of the first polypeptideis fused with the tail end N of the second polypeptide to obtain the long-acting nerve growth factor which has an in-vitro half-life period exceeding 14 hours, and is relatively high in biological activity.

0/0