The invention provides an optimized generator tripping method and device for a regional power grid abundant electric power direct current delivery system. The method comprises the following steps: acquiring the total quantity of sets required to be cut off in a regional power grid after a direct current block fault; cutting off wind turbine generators with bus transient voltage variation larger than or equal to high pressure resistant capability at a wind turbine generator side in a direct current near zone before and after the direct current block fault, and calculating capacity of the sets required to be cut off complementally in the regional power grid of a security control system and the total quantity of sets required to be cut off in a provincial power grid; and cutting of within-province sets in a provincial power grid generator tripping sequence. The optimized generator tripping method and device for the regional power grid abundant electric power direct current delivery systemare strong in operability, can be used for establishing security control measures of the actual extrahigh voltage/high voltage direct current power transmission system and guiding reliable operationof the extrahigh voltage/high voltage direct current power transmission system and has great practical significance on safe and stable operation of an AC-DC hybrid power grid after the extrahigh voltage/high voltage direct current power transmission system is put into operation.