The invention provides a protection base of an upright-type breakwater based on local block stone grouting, and belongs to the technical field of breakwater foundation bed protection. The protection base comprises a riprap base layer, an inverted filter layer, a base protection layer and a foot protection layer. The inverted filter layer is laid on the upper end face of the side, close to the sea,of the riprap base layer. The base protection layer is laid on the upper end face of the inverted filter layer. The foot protection layer is arranged at the lower end of the base protection layer. The base protection layer and the foot protection layer are both formed by piling up block stone. Grouting materials are arranged between the block stone. The protection base is convenient to construct,high in stability, high in adaptability, good in water permeability and convenient to maintain.