The invention discloses a multi-fault static safety analysis method taking crossing and power transmission channels into consideration. On the basis of normalization N-1 scanning, a crossing and important power transmission channel concept is introduced into an expected fault set to form a corresponding multiple combined fault; the on-off sensitivity of a circuit is calculated on the basis of a power flow matrix algorithm, and a circuit on-off fault influence domain is formed; then simulation on-off is performed on the crossing and important power transmission channel multiple faults, and a circuit power flow and heavy load out-of-limit check after faults are quickly estimated, and suspicious serious fault sets are screened; and the serious fault sets are subjected to detailed analysis andcalculation by adopting an alternating current power flow algorithm, so that static safety pre-warning information which can be used for reference for a dispatcher in making crossing and important power transmission channel multi-on-off accident decisions is provided.