The invention provides a moisturizing spot-removing facial cleanser and a preparation method thereof. The moisturizing spot-removing facial cleanser comprises the following raw materials (by weight):10-13 parts of a Plukenetia volubilis Linneo extract, 6-8 parts of a blueberry extract, 2-4 parts of sour carambola juice, 3-5 parts of a dahurian angelica root extract, 4-6 parts of coconut milk, 3-5parts of sorbitol, 7-9 parts of pearl powder, 1-3 parts of hyaluronic acid, 11-13 parts of polyglycerol fatty acid ester, 1-2 parts of rhamnolipid, 1-3 parts of marine lysozyme, 1-3 parts of chitosanand 1-2 parts of azone. The moisturizing spot-removing facial cleanser has efficacy of supplementing water and moisturizing, nourishing skin and beautifying the features, removing spots and whiteningthe skin when being used for a long time.