The present invention provides a voice information transmission method and device in a virtual reality scene. The voice information transmission method comprises a step of transmitting first voice information to an information receiver with an established data connection during the operation process of a target virtual reality scene, a step of receiving e second voice information that is sent by the information receiver according to the first voice information, a step of judging whether the target virtual reality scene is still running or not according to an identifier of the target virtual reality scene in the second voice information, displaying first reply prompt information in the target virtual reality scene if so. According to the voice information transmission method and device, thevoice information transmission of a user in the virtual reality scene can be effectively achieved, and the real-time interaction requirement of the user in the virtual reality scene is satisfied.