The invention relates to a simulation circuit module fault diagnosis method and aims to solve a problem of low circuit module fault diagnosis accuracy caused by lack of fault samples in the actual simulation circuit module fault diagnosis process. The method comprises steps that S1, a simulation circuit is subjected to functional module division; S2, through a simulation experiment, a pulse signalis inputted to the circuit, the detection rate of each node of each module in a normal state is obtained, and the detection rate of each node of any module in a fault state is obtained; S3, fault detection on each module of the actual circuit is performed; S4, reliability is configured for the detection result of each module according to the detection rate, and the credibility is taken as an evidence m1; S5, a pulse signal is replaced with a frequency sweeping signal, the steps 2-4 are repeated to get an evidence m2, after the m1 and the m2 are fused through the D-S evidence theory, the faulty module is located. The method is applied to the simulation circuit module fault diagnosis field.