The invention relates to a testing device and method for analyzing the influence of ground subsidence on pipe-soil interaction. The testing device comprises a model box, a soil body, a pipeline, a ground subsidence analog device and a pipe-soil measuring device, wherein the ground subsidence analog device comprises water bags, a water pipe, a concentrator, a water main, a switch, an adjusting valve, a flowmeter, a water collector and a deformation compatibility plate; the pipe-soil measuring device comprises a distributed sensing optical fiber, an OBR backlight reflectometer, a thin film pressure sensor, a data acquisition instrument, a pipeline subsidence mark, a laser displacement meter, a soil body subsidence mark, a high resolution digital camera and a computer; the water bag array isarranged according to the subsidence type; the pipeline is fixed at a preset depth; all the measuring instruments are connected to the computer, and data are acquired by software; the soil body prepared in advance is filled in the model casing; and water is drained from the water bags, the acquisition is stopped until the deformation of the pipeline and the soil body is basically stable, and the data are stored.