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发明授权
CN108904496B 用于治疗丙型肝炎感染的药物组合物 有权 转让

用于治疗丙型肝炎感染的药物组合物
摘要：
本发明涉一种用于治疗丙型肝炎病毒感染的药物组合物和单位剂型，所述组合物和单位剂型包含治疗有效量的KW136(N‑[(2S)‑1‑[(2S)‑2‑{4‑[7‑(4‑{2‑[(2S)‑1‑[(2S)‑2‑[(甲氧基羰基)氨基]‑3‑甲基丁酰基]吡咯烷‑2‑基]‑1H‑咪唑‑4‑基}苯基)‑2H‑1,3‑苯并二恶茂‑4‑基]‑1H‑咪唑‑2‑基}吡咯烷‑1‑基]‑3‑甲基‑1‑氧代丁烷‑2‑基]氨基甲酸甲酯二盐酸盐，式II)和至少一种药学上可接受的赋形剂，以及用于制备所述药物组合物和单位剂型的方法。
摘要（英）：

The invention relates to a drug composition for treating hepatitis C infection and a unit dosage form. The drug composition and the unit dosage are prepared from KW136(N-[(2S)-1-[(2S)-2-{4-[7-(4-{2-[(2S)-1-[(2S)-2-(methoxycarbonyl)amino]3-methylbutyryl]pyrrolidine-2-yl)-1H-imidazole-4-yl}phenyl}-2H-1,3-benzodioxole-4-yl]-1H-imidazole-2-yl}pyrrolidine-1-yl]-3-methyl-1-oxobutane-2-yl]methyl carbamate dihydrochloride, a compound as shown in a formula (II) and at least one pharmaceutically acceptable excipient which are in therapeutically effective amounts. The invention also discloses a method for preparing the drug composition and the unit dosage form.

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