The invention discloses a total chlorine free disease-prevention female sanitary napkin. The total chlorine free disease-prevention female sanitary napkin is prepared through following steps: cotton stalk, bamboo willow, mulberry shoot, and bagasse are adopted as raw materials, oxygen with nucleophilic activity obtained ultraviolet light catalytic of hydrogen peroxide is adopted for softening anddecolouring, and untwining of slurry is adopted to obtain peroxided cellulose fluff pulp; cotton linter is adopted to prepare thin soft wet paper high in toughness, hygroscopicity, and air permeability to replace non-woven fabrics as internal and external layer thin linings; at the same time, total chlorine free cotton stalk slurry is adopted to prepare a methyl cellulose water-retaining agent excellent in water retaining capacity; sanitary napkin paper is adopted to prepare the total chlorine free disease-prevention female sanitary napkin of large, medium, and small sizes, wherein the surfacelayer of the total chlorine free disease-prevention female sanitary napkin is dry and refresh, the middle layer possesses gas permeability and water absorbing capacity, the bottom layer possesses gaspermeability, and the total chlorine free disease-prevention female sanitary napkin is capable of disinfecting, deodorizing, and killing bacteria.