The invention discloses time automatic compensation centrifugation system and method. The centrifugation system and method comprises the step 1 of placing a cell into a centrifugation cavity and starting a centrifugation machine; the step 2 of starting to measure temperature of the centrifugation cavity through a temperature sensor connected with the centrifugation cavity when the centrifugation cavity operates stably; the step 3 of calling a data module to calculate actual centrifugation time according to received measured temperature of the centrifugation cavity; the step 4 of correcting original preset centrifugation time of the centrifugation machine to the actual centrifugation time; and the step 5 of keeping the centrifugation machine running to the actual centrifugation time to stoprunning. Same blood sample is centrifuged at different temperatures, the required different centrifugation time is recorded as an adjusting basis, a time automatic compensation mode is adopted, the influence of temperature change on centrifugal effect can be effectively reduced or eliminated, and optimal separation effect of a blood cell can be achieved.