The invention discloses a multi-purpose safety frame for substation equipment maintenance. The multi-purpose safety frame comprises a base and a safety frame body. Pulleys and lifting columns are installed at the bottom of the base, the base is internally provided with a hydraulic cylinder, and two sets of telescopic rods are installed on the hydraulic cylinder. A first guard rail, a second guardrail and a third guard rail are installed on the three sides of the safety frame body. A lamp post is installed at one end of the first guard rail, and a lamp is rotatably installed at the top of thelamp post. The first guard rail is provided with a plurality of object placing buckets, and the object placing buckets are equidistantly arranged on the first guide rail with different opening shapesand different depths; the second guard rail is provided with a controller, the second guardrail is hinged to a working table, and the third guard rail is provided with an inner compartment; and a single-opened protective door is installed between the first guard rail and the third guard rail. The multi-purpose safety frame can provide a good working platform and is equipped with different tools according to actual conditions, a lighting function is added, and the multi-purpose safety frame can cope with different working environments and ensures that work is carried out in an orderly manner.