The invention relates to an energy supply protection circuit. The energy supply protection circuit comprises a circuit input port used for connecting an energy supply circuit, a circuit output port used for connecting a load, a power switch connected in series between the circuit input port and the circuit output port, and a power switch control circuit, wherein the power switch control circuit isin control connection with the power switch, a voltage sampling circuit, a voltage integral operation amplifying circuit and a controller are further comprised, the voltage sampling circuit is in sampling connection with the circuit output port and is used for obtaining the voltage of the circuit output port, a signal output end of the voltage sampling circuit is connected with an input end of the voltage integral operation amplifying circuit, an output end of the voltage integral operation amplifying circuit is connected with the power switch control circuit, and the controller is connectedwith the input end and the output end of the voltage integral operation amplifying circuit. The energy supply protection circuit is advantaged in that through controlling the conduction degree of thepower switch connected in series between the energy supply circuit and the load, so the purpose of stabilizing and limiting the output voltage of the energy supply circuit is achieved, and the load iseffectively protected.