The present invention discloses a friction nanometer generator based on a 3D printing technology and a manufacturing method thereof. A 3D printer is employed for manufacturing, the generator comprisesframes, a pedestals, a handle and friction units, the frame comprises fixed frames and mobile frames, the fixed frames are arranged on the ground, the mobile frames are respectively arranged at the outer sides of the fixed frames, the pedestals comprises mobile pedestals and fixed pedestals, there are the plurality of mobile pedestals and fixed pedestals, each mobile pedestal and each fixed pedestal are arranged on the frame at equal intervals, the two ends of the fixed pedestals are fixedly connected with the fixed frames, the two ends of the mobile pedestals pass through the fixed pedestalsand are fixedly connected with the mobile frames; and the friction units are respectively arranged at lower end faces and the upper end faces of the adjacent pedestals. The friction nanometer generator can improve the output performance of the friction nanometer generator and can reduce the manufacturing cost of the friction nanometer generator.