An embodiment of the invention discloses a control system of an ultraviolet light-emitting diode light source. The control system comprises an ultraviolet light-emitting diode UVLED light source module, a current acquisition module, a set current output module, a comparison module and a pulse width modulation PWM module, wherein the UVLED light source module is used for emitting ultraviolet light;the current acquisition module is electrically connected with the UVLED light source module, and is used for acquiring an operating current of the UVLED light source; the comparison module is electrically connected with the set current output module and the current acquisition module respectively, and is used for outputting a set current and an operating current to the comparison module; the comparison module is used for generating a control signal according to the set current and the operating current; the comparison module is electrically connected with the PWM module, and is used for transmitting the control signal to the PWM module; and the PWM module is configured to generate the PWM driving signal according to the control signal, and driving the UVLED light source by means of the PWM driving signal. The control system provided by the embodiment of the invention can solve the problem of short light attenuation cycle of the UVLED light source caused by the existing control methodsof the UVLED light source.