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发明公开
CN108976128A 一种2-硝基-2-甲基-1-丙醇晶体的制备方法 有权

一种2-硝基-2-甲基-1-丙醇晶体的制备方法
摘要：
本发明提供了一种2-硝基-2-甲基-1-丙醇晶体的制备方法，所述方法通过采用2-硝基丙烷与多聚甲醛的反应来制取2-硝基-2-甲基-1-丙醇，并通过采用酸性固体催化剂来除去残留的甲醛，以及采用环己烷二次纯化产物，从而获得了2-硝基-2-甲基-1-丙醇晶体，其纯度高达99.8％-99.99％且甲醛残留量为5-200ppm。此外根据本发明的方法的基于2-硝基丙烷的反应转化率可达98％至99.7％，二次纯化后的最终收率为90％至97％。
摘要（英）：

The invention provides a preparation method of a 2-nitro-2-methyl-1-propanol crystal. According to the method, 2-nitro-2-methyl-1-propanol is prepared through a reaction between 2-nitropropane and paraformaldehyde, the residual formaldehyde is removed with an acidic solid catalyst, and the product is subjected to secondary purification with cyclohexane so as to obtain the 2-nitro-2-methyl-1-propanol crystal, wherein the purity is up to 99.8-99.99%, and the residual formaldehyde is 5-200 ppm; and the conversion rate of the reaction based on 2-nitropropane can be 98-99.7%, and the final yield after the secondary purification is 90-97%.

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