The invention discloses a hexagonal twelve-strand anti-twisting steel wire rope. The rope comprises twelve rope strands of the same structure, and six rope strands twisted leftward and six rope strands twisted rightward are entwisted mutually to form the cross section of an orthohexagonal shape; six of the twelve rope strands are arranged in the rope in an annular mode, and a central rope strand is arranged in a middle gap of the six rope strands; six cotton ramie silk woven strips which are twined in an annular arrangement mode are arranged on the periphery of the central rope strand and subjected to oil soaking treatment, the insides of the woven strips adsorb oil, and after extrusion, the oil can be leached. The rope strands are composed of two parts, nineteen inner layer steel wires with shorter diameters are arranged in the rope, and the flexibility of the steel wires can be kept; twelve outer layer steel wires with larger diameters are arranged on the outer portion of the rope, the stretching intensity and extreme fatigue resistance of the steel wire rope are kept, and through the setting of the diameter ratio of all steel wire rope bodies, the integral intensity and strengthstretching of the steel wire rope can reach the best state.