The invention discloses a long-edge profiling bending machine. The long-edge profiling bending machine comprises a base assembly, a first profiling bending mechanism, a second profiling bending mechanism and a conveying and pressing assembly. The first profiling bending mechanism and the second profiling bending mechanism are of the same structure and are arranged symmetrically. The first profiling bending mechanism comprises a profiling bending base, an upper supporting plate, a lower supporting plate, side fixing plates, an upper pressing mechanism and a jacking mechanism. The upper pressingmechanism comprises upper pressing gas-liquid pressure cylinders, an upper pressing mounting plate, an upper pressing lifting plate, a synchronous shaft, an upper die plate and an upper female die plate. The jacking mechanism comprises a jacking cylinder, a jacking mounting plate and a lower die plate. The base assembly comprises an upper base plate, a lower base plate and a sliding rail. The sliding rail is horizontally arranged on the upper base plate. A sliding block is arranged at the bottom of the profiling bending base of the second profiling bending mechanism. By adoption of the long-edge profiling bending machine, one-time profiling, bending, conveying and pressing of plates are achieved, plates with V-shaped grooves are machined synchronously on both sides, the profiling bendingefficiency is high, and the production efficiency is improved.