The invention discloses a preparation method suitable for mixed compression of an aluminum nitride ceramic sheet and an alumina ceramic sheet. The preparation method comprises the following steps: (1), preparation work; B, preparation of an aluminum nitride ceramic sheet board according to a process flow: completing a line, performing solder resistance and surface treatment until a bonding process; C, bonding: aligning the prepared alumina ceramic sheet and the completed aluminum nitride ceramic circuit board with a designed graphic, and performing fitting and fixation; and D, plate press: placing a pre-made smelting tool into a press. According to the method, the process from preparation completion to solder resistance of the aluminum nitride ceramic sheet can be finished according to thepreparation process of normal ceramic plate products, grafting to the cut alumina ceramic sheet can be performed through high temperature glue, then pressure bearing can be conducted through the worksmelting tool, and then the two materials are bonded together completely through high temperature and high pressure of the vacuum press; and then high temperature curing is performed, and finally theobtained material is subjected to 350 DEG C high temperature and a tin applying test, so that SMT sticking or binding requirements of a customer are fully met.