The invention discloses a capsule drug delivery device. The device comprises a drug delivery main body and a movable drug mouth, the two sides of the top of the drug delivery main body are provided with drug mouth installation trays, the movable drug mouth is installed on the top of the drug delivery main body and is located between the two drug mouth installation trays, the two ends of the movable drug mouth are respectively movably connected to the two drug mouth installation trays, and the inside of the drug delivery main body is of an up and down structure and provided with a one-way air spray valve and a flexible air spray ball. The device is reasonable in structure design, through the design of the two parts of the drug delivery main body and the movable drug mouth, the one-way air spray valve and the flexible air spray ball are designed in combination in the drug delivery main body, drug powder in a capsule medicament is poured into the movable drug mouth, and the drug powder inthe movable drug mouth can be sprayed into the mouth of a patient by pressing the flexible air spray ball, and enters the inside of a human body as the breathing of the patient, thereby avoiding theproblems that the patient difficultly swallows the capsule medicament, and the drug powder in the movable drug mouth is returned to the flexible air spray ball to cause damage to the drug powder.