The invention discloses application of a Ni-Nb binary alloy to tellurium corrosion resistance. A new purpose of application of the Ni-Nb binary alloy serving as a tellurium corrosion resistance material to the tellurium corrosion environment is disclosed for the first time, and when the Ni-Nb binary alloy is applied to the tellurium corrosion environment, the Nb element in the alloy and the tellurium element on the surface of the alloy can be reacted to form a relatively dense niobiumtelluride layer, further diffusion of the tellurium element into the alloy along the crystal boundary is resisted, meanwhile, the niobiumtelluride layer can resist outward diffusion of the metal in a base body, and accordingly other telluride products cannot be formed. The Ni-Nb alloy has good processing performance, can be directly machined into a component and can also be made into welding materials or powder for conducting coating treatment on other alloys. The Ni-Nb alloy has an excellent tellurium corrosion resistance character and also has an excellent high-temperature molten salt corrosion resisting character and a high-temperature strength character, and therefore the component or a coating made of the Ni-Nb is particularly suitable for being applied to molten salt reactors, sodium-cooled fast reactors and other severe environments where high-temperature molten salt corrosion and telluriumcorrosion exist at the same time.