The invention discloses a hand-held clothes cutting device with a positioning ranging rod, and relates to the technical field of clothes cutting. The hand-held clothes cutting device with a positioning ranging rod includes a casing, wherein a first groove is formed in one end of the casing; a mounting box is arranged in the first groove; two sides of one end of the mounting box are movably connected to the casing through a transmission shaft; one end of the transmission shaft is fixedly connected with the mounting box, and the other end of the transmission shaft is movably connected to the casing; the transmission shaft is axially connected with a variable gear fixedly; a second motor is arranged at one side of the variable gear; and the second motor is fixedly connected with the casing. The hand-held clothes cutting device with a positioning ranging rod can drive the mounting box to rotate by setting the second motor and the transmission shaft to achieve the aim of shrinking a cutter,can drive the cutter to rotate through cooperative setting of a first rotating shaft, a second rotating shaft, a third rotating shaft and a belt to achieve the aim of cutting, can measure clothes bysetting the ranging rod, thus being convenient for measuring the size while cutting.