The invention belongs to the technical field of petroleum exploitation, and relates to how to quantitatively estimate covering layer sealing performance in processes of carrying out a CCUS project. Acovering layer sealing performance prediction method of the Ordos basin is provided and comprises steps of selecting a production well of a to-be-estimated region, and reading the starting depth valueX1 and the thickness of a long 4+5 covering layer on a well logging curve; carrying out segmentation and fitting the interval transit time curve of the long 4+5 covering layer, and calculating the interval transit time value corresponding to the interval transit time curve; and substituting the read thickness value h and the corresponding interval transit time of the long 4+5 covering layer intoa formula, calculating a composite displacement pressure value P and evaluating the sealing performance of the covering layer by use of the P. According to the invention, the prediction method is simple and convenient; it can be avoided that a plenty of time and cost are used for obtaining horizontal displacement pressure and vertical displacement pressure through a high-pressure mercury intrusionmethod or a breakthrough pressure method; and inaccuracy caused by that fact the horizontal displacement pressure measured by the high-pressure mercury intrusion method or the vertical displacement pressure measured by the breakthrough pressure method is used as an index to measure the sealing performance of the covering layer can be avoided.