The invention discloses a split type instrument ball valve with the long service life, and relates to the technical field of instrument valves. The split type instrument ball valve with the long service life comprises a valve body pipeline, a valve base and a control part, wherein the valve base and the control part are connected to the valve body pipeline. The control part comprises a control ball and a control handle. A control rod is connected to the valve base in a rotating mode, the control handle is integrally arranged on the control rod, and one end of the control handle penetrates through the control rod to form a locking rod. Two locking blocks which are used for limiting the rotation angle of the locking rod are arranged on the valve base, and a right angle is formed between thetwo locking blocks and the control rod. Locking parts which are used for clamping the locking rod are arranged on the portions, corresponding to the locking blocks, of the valve base, and the two locking parts are arranged in the mode of corresponding to the locking blocks and can lock the control handle. The phenomenon that due to the fact that small animals in the outside world impact on the valve, or the valve is subjected to misoperation of irrelevant personnel, the valve is opened and closed is avoided, the phenomenon that utilization of media in the pipeline is affected is avoided, and the locking and unlocking process is relatively convenient and fast.