The invention provides an anti-vibration device for a transmission line. The anti-vibration device comprises a pre-stranded wire clamp and a damping wire. The longitudinal section of the pre-twisted wire clip is an integrally formed support with a rectangular shape; The longitudinal direction of the support part is sequentially provided with a transverse groove supporting the transmission line from the upper end surface to the inner side of the lower end, the transverse arc-shaped through hole fixing the inner prestranded wire, the transverse rectangular through hole fixing the outer prestranded wire and the transverse circular through hole fixing the damping wire. The technical proposal provided by the invention can effectively suppress the breeze vibration of the conductor and avoid thefatigue broken strand of the conductor, and has the following characteristics: the grip is reliable and the wire clip is effectively prevented from slipping; The resonant frequency range is wide, which can cover the whole frequency range of breeze vibration. The damping performance is good and the energy consumption is higher than that of anti-vibration hammer. Easy to install, can be installed directly by hand; Maintenance-free, no possibility of loosening and slipping, no need for regular maintenance, long in service life.