Disclosed is a detachable endoscopic anastomosis clamp, relating to the technical field of the medical apparatus and instruments and solving the problems in the prior art that the anastomosis clamp cannot be easily removed and the clamping force is low. The detachable endoscopic anastomosis clamp comprises occluding members (1,3) and elastic members (2,4), wherein at least two occluding members (1,3) and at least two elastic members (2,4) are provided; the end portions of the occluding members (1,3) and the end portions of the elastic members (2,4) are connected in sequence to form a plurality of connecting portions (11); and at least one of the connecting portion (11) of the plurality of connecting portions is a detachable connecting portion. An easy and convenient disassembling and removing can be implemented after operation by using the anastomosis clamp.