The invention discloses an oblique-drum vacuum solid fermentation tank internally provided with a heat-exchange helical blade. The oblique-drum vacuum solid fermentation tank internally provided withthe heat-exchange helical blade comprises a tank body and a base, wherein a hollow stirrer used for stirring and mixing is arranged on the inner wall of the tank body, and a bearing rail and a drivengear which surrounds the tank body are arranged at the front end of the tank body; a hollow radical shaft is arranged at the bottom end of the tank body, and a bearing is arranged outside the hollow radical shaft; a vacuumizing rotating connector is arranged at the top end of the tank body, and the vacuumizing rotating connector is communicated with a vacuum pump; a first supporting base, a secondsupporting base and a motor installation base are arranged on the base, a bearing wheel matched with the bearing rail is arranged on the first supporting base, the second supporting base is movably connected with the bearing, a heat-exchange medium rotating connector is arranged at the tail end of the bearing, a driving motor is arranged on the motor installation base, and a driving gear matchedwith the driven gear is arranged on the driving motor. The oblique-drum vacuum solid fermentation tank internally provided with the heat-exchange helical blade has internal and external double heating/cooling, double stirring and back mixing functions, capable of completing vacuum drying at the same time, and is suitable for multi-purpose non-in-place sterile solid fermentation production.