The invention discloses a titanium dioxide sampling device in the technical field of sampling detection equipment. The device comprises a sampling rod, a sampling cylinder and a filling rod; the sampling cylinder is arranged at one end of the sampling rod; an opening of the sampling cylinder faces to the other end of the sampling rod; a filling head is arranged at the end part of the filling rod;and the filling head can be inserted into the sampling cylinder to seal the sampling cylinder. The device has the beneficial effects that the sampling cylinder is temporarily plugged by utilizing thefilling rod, so that the sampling cylinder is not affected by a shallow layer material when being inserted into the deep part of the material to perform sampling; during sampling, the filling rod is drawn out, and then the sampling cylinder is pulled out; the whole device is simple in structure and convenient to use, and is suitable for sampling in large industrial equipment; and a sample in a designated position can be extracted in a small packaging bag and the like, so that the sampling is more convenient and more scientific.