The embodiment of the invention discloses a gastric cancer gene mutation and drug interpretation multi-database interactive system, which comprises a gastric cancer gene mutation information database,a gastric cancer drug treatment database and a gastric cancer literature information database. Each database is used for storing corresponding data; gastric cancer drug treatment database includes gastric cancer gene mutation and drug treatment approval information database, gastric cancer gene mutation and drug treatment expert consensus information database and gastric cancer gene mutation anddrug treatment clinical trial information database. By establishing a multi-database interaction system, the data of gastric cancer gene mutation and drug-related data can be stored. The interactive system has perfect data quantity and is easy to use.