The invention relates to the field of rail passenger car accessories, in particular to a rail passenger car cable safety sealing device. The purpose of the invention is to provide a cable safety sealing device for railway passenger cars with simple structure, convenient installation and anti-vibration; The cable safety sealing device comprises a frame, a pressing plate and a bottom plate; the bottom plate is fixed on the back surface of the frame and seals the back surface of the frame; the pressing plate is arranged in the frame; The pressing plate is movably connected with the bottom plate through bolts, and a rubber block is arranged between the pressing plate and the bottom plate; The bottom plate is provided with a plurality of first cable holes, the rubber block is provided with a plurality of second cable holes, and the pressure plate is provided with a plurality of third cable holes. Each first cable hole, the second cable hole and the third cable hole are concentrically arranged to form a cable hole, and each cable hole is formed into a cable hole group according to different apertures. The cable safety sealing device has the characteristics of simple structure, simple andconvenient installation, earthquake resistance and high protection level.