The invention belongs to the field of pharmaceutical preparations, and in particular relates to an acitretin suspension and a preparation method of the acitretin suspension. The acitretin suspension disclosed by the invention has auxiliary materials of one or more of powdered cellulose, siliconized cellulose or microcrystalline cellulose, one or more of calcium ascorbate, sodium ascorbate, ascorbyl palmitate and ascorbic acid, one or more of gum tragacanth, carrageenan, gelatin, gum arabic, locust bean gum and guar gum, and one or more of a glucose binder, glucose syrup dry powder, starch syrup dry powder, maltodextrin, dextrin and starch. The acitretin suspension prepared by the invention is obviously improved in dissolution rate of acitretin, the acitretin is stably suspended in an aqueous solution by solid particles, and has good physical stability. Furthermore, the acitretin contains no surfactant to reduce toxicity of drug-related preparations to human bodies. The acitretin suspension disclosed by the invention is convenient for large-scale industrialization production in the production, and realizes individual administration clinically in application conveniently.