The invention relates to a plasma-clad copper-based shape memory alloy anti-cavitation coating and a preparation method thereof, and belongs to the technical field of alloy coatings. The plasma-clad copper-based shape memory alloy anti-cavitation coating comprises the following compositions of, by mass, 64.5-66.5% of Cu, 11-12.5% of Al, 16.5-21.5% of Zn and 3-4.5% of Mn. The plasma-clad copper-based shape memory alloy anti-cavitation coating has the smooth surface, has no cracks, pores and other defects, and has good cavitation resistance and wear resistance. According to the preparation method of the plasma cladding copper-based shape memory alloy anti-cavitation coating, the technological process is simple, the cost is low, and the preparation method is suitable for mass production, thespraying coating prepared through the method and a matrix are in metallurgical combination, a combination line is clear, the structure of a cladding material on a substrate is dense, and the good cavitation resistance is achieved.