A high-power low-frequency cable program-controlled wheel matrix switch conversion system comprises a wheel matrix switch female head, a wheel matrix switch male head, program-controlled drivers (5) and an upper computer. The wheel matrix switch female head comprises N insulating rotating disks (4), and a row-type base (6); a program-controlled driver (5) is installed at the center of each insulating rotating disk (4), and the upper computer drives the program-controlled drivers (5) according to the input contact relationship. After the program-controlled drivers (5) control the insulating rotating disk (4) to rotate to the corresponding angle and position, the upper computer controls the wheel matrix switch male head and the wheel matrix switch female head to be butted and locked to forman N-level power path. The invention gates arbitrary core wires through a program-controlled wheel structure, realizes the capacity of batch processing of low-frequency cable paths and expansion of test points, and breaks through the power capacity limitation of switches of traditional relays, integrated devices and the like.