The invention provides a plant-growing blanket, application thereof and a slope ecological restoration method, and relates to the technical field of ecological restoration. The plant-growing blanket provided by the invention comprises a substrate layer and a pipe network layer, the substrate layer comprises plant seeds and a growth substrate, and the pipe network layer is laid inside the substratelayer. The pipe network layer is laid inside the substrate layer, when the plant-growing blanket needs watering, large-area watering of the planting blanket can be achieved only by connecting a watersource, thereby reducing the burden of watering and curing, achieving long-term stability of greening and effectively preventing slope instability. In addition, the growth substrate in the substratelayer can provide nutrients needed for plant growth, thereby creating a growth-friendly environment for plants. The combination of the substrate layer and the pipe network layer is more prone to germination and growth of plant seeds, the survival rate is high, sand blow by wind and loss of water and soil can be effectively prevented, rock and road slopes are quickly re-greened, and a harmonious natural landscape is shown.