The invention discloses a nonlinear anti-interference control method and device for an electronic throttle system. On the basis of a system control model and the continuous finite-time anti-interference control method, the control device and a design method for a tracking control problem of electronic throttle valve opening are designed. The invention designs an observation method and device for multi-source interference, uncertainty and nonlinearity caused by factors such as an intake air flow, friction, spring torque and backlash, and so accurate estimation of lumped interference and systemstate variables is realized in finite time. According to the invention, a continuous terminal sliding mode control method and an output feedback control method are combined to effectively suppress adverse effects of the multi-source, uncertainty and nonlinearity in the electronic throttle system. Therefore, the accurate tracking control of the electronic throttle valve opening is realized in the finite time when the system is disturbed, the hardware cost of the system is reduced, and the dynamic characteristics, steady state characteristics and anti-interference ability of the system are improved.