The invention relates to the technical field of power protection materials, and particularly relates to a protective coating for high-voltage and high-frequency power equipment. The protective coatingcomprises the following components: a pure acrylic emulsion, fluorosilicone resin, polyvinylpyrrolidone, fillers, an anti-radiation additive, sodium nitrite, hydroxypropyl methyl cellulose ether, nonylphenol polyoxyethylene ether, an antiseptic bacteriostat and a defoamer, wherein the structure of the anti-radiation additive comprises a superhard base core composed of inorganic fillers, anti-radiation functional particles distributed on a surface of the base core, and a polyamide-imide film layer coating an outer layer of the anti-radiation functional particles; the fillers contain titanium dioxide, lithium-based bentonite and palygorskite powder; the antiseptic is isothiazolinone or thiophanate methyl; and the defoamer is a silicone defoamer or a mineral oil defoamer. The coating provided by the invention has advantages of high film strength, good adhesion, relatively good corrosion, rust and corrosion resistances, and excellent anti-radiation performance.