The invention discloses a garment fabric printing and setting device without removing an ink cartridge. The device comprises a body, supporting columns, a framework, the ink cartridge, a hot air blower and a slideway. A conveying belt is arranged on the lower part of the inside of the body, and a driving wheel is mounted on the left side of the inner side of the conveying belt. A motor is connected on the outer side of the driving wheel. The supporting columns are arranged in the middle of the conveying belt. A driven wheel is arranged on the right side of the inside of the conveying belt. Theframework is installed on the upper part of the inside of the body, and the motor is arranged inside the framework. A rotating shaft is arranged on the right side of the motor, and a dyeing wheel isarranged on the right side of the rotate shaft. The ink cartridge is arranged on the upper part of the outer side of the body, and an ink pouring port is arranged above the ink cartridge. According tothe garment fabric printing and setting device without removing the ink cartridge, the conveying belt is arranged on the blower part, and only the fabric requiring printing is put on the conveying belt in operation and the machine can perform printing and drying so that the degree of mechanization is high and the manpower can be saved.