The present disclosure relates to a driving method of a display device, a driving device, a display device, and a computer-readable medium. The display device includes a backlight module including a plurality of backlight partitions. The driving method comprises the following steps: determining a first backlight signal value of the plurality of backlight regions according to an input gray value ofa pixel in an image to be displayed; Determining a second backlight signal value according to the first backlight signal value and a preset backlight spread function; And driving the backlight moduleto emit light using the second backlight signal value.