The invention provides an experimental device for simulating the mine lifting operation in deep-sea mining, relates to the technical field of deep-sea mining experimental equipment, and solves the dynamic characteristics of a spatial structure when the mine lifting operation in deep-sea mining is simulated. The device comprises an experimental box, a wave generation mechanism, a flow speed controlmechanism, a simulated mining mechanism and a monitoring mechanism; the wave generation mechanism comprises a control box and a wave pushing plate, and is used for simulating wave; the flow speed control mechanism comprises a water pump, a motor, a grid plate and a manifold; the flow speed and the flow are adjusted by utilization of the grid plate and the manifold; the simulated mining mechanismcomprises an experimental boat model, a mine lifting pipe, a mixture box, an ore pulp pump, a feeding pipe and a return pipe, and is used for simulating the mine lifting operation state; and the monitoring mechanism comprises a wave height measurer, a displacement sensor, a flow speed measurer and an image acquisition device, and is used for detecting the dynamic influence of the wave height and the flow speed on the simulated mining mechanism in the mining process, in particular the mine lifting operation. The device further has the advantages of being in multi-parameter real-time monitoring,low in manufacturing cost, simple to operate and the like.